Composition: N-Acetylcysteine, Ascorbic Acid (Vitamin C), Alpha-Lipoic Acid, Sorbitol, Microcrystalline Cellulose, Talc, Magnesium Stearate, Cutin, Maize Starch, Dicalcium Phosphate.
NAC (N-acetylcysteine)
It is the N-acetyl derivative of the sulphur-containing amino acid L-cysteine, providing increased stability and biovailability compared to the latter.
Cysteine is a non-essential amino acid needed for several biochemical processes – for example, in the formation of the protein keratin, which contains a large amount of sulphur, mainly in the form of the sulphur-containing amino acid cysteine. Cross-linking via dilsulfide bridges (S-S) provides the keratin structure with unique solidity, cohesion and strength.
In addition, N-acetylcysteine is a precursor to the tripeptide glutathione (GSH), the main endogenous antioxidant, chiefly produced by the liver. Numerous studies suggest that supplementation with N-acetylcysteine boosts endogenous glutathione synthesis and nitric oxide (NO) production.
It also exhibits a remarkable direct antioxidant action, based on a free nucleophilic thiol-containing group which can selectively interact with the electrophilic groups of oxidative free radicals, and has a chelating action on heavy metals, thereby facilitating their elimination.
Vitamin C (ascorbic acid)
Vitamin C (also known as ascorbic acid) is a substance performing countless functions. It is essential for the entire body, as it serves as a key cofactor in many enzymatic reactions.
According to several sources, NAC supplementation should always be combined with a proper intake of this vitamin, in order to strengthen the effects.
Vitamin C is a water-soluble vitamin that is not stored in the body and has a wide-ranging action. Since the human body cannot synthesize it, it must be included in the daily diet.
A varied diet ensures a proper intake of this vitamin. Nevertheless, the modern lifestyle along with other factors may require additional supplementation – for example, to allow major doses of vitamin C to be taken, as, according to several studies, they are definitely beneficial.
It should be pointed out that vitamin C is almost completely destroyed or washed out during food preparation and storage. So fresh fruit and vegetables are key to any diet programme.
Alpha-Lipoic Acid
This substance exhibits marked and proven antioxidant properties and also acts by physiologically restoring other antioxidants (glutathione, NAC, vitamins C and E) which have functioned against free radicals.
It prevents LDL cholesterol oxidation and boosts cellular energy production by increasing endogenous ATP.
It improves the absorption of some nutrients and is involved in glucose metabolism regulation by decreasing sugar absorption. It also has a chelating action on heavy metals.
Quantities per maximum recommended daily dose (1 tablet)
| N-Acetylcysteine |
500mg |
| Vitamin C |
250mg (312,5%NRVs*) |
| Alpha-Lipoic Acid |
150mg |
*NRVs: Nutrient Reference Values
Recommended intake: 1 tablet daily, with plenty of water.
The tablet can be taken at any time of the day, with or between meals.
The tablets are scored in the middle, so they can easily be split into two equal halves.
